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Drug Prescribing Patterns for Chronic Kidney Disease in a Tertiary Care Hospital of Bangladesh

*Dema TS,1 Ahmed AU,2 Roy AS,3 Begum SA,4 Sattar S,5 Afrose R,6 Ferdous J,7 Razia S,8 Hussain MA,9 Banu TA10

 

  1. *Dr. Taslima Sultana Dema, Lecturer, Department of Community Based Medical College Bangladesh, Mymensingh. taslimadema@gmail.com
  2. Aftab Udding Ahmed, Professor and Head (rtd), Department of Pharmacology, Mymensingh Medical College, Mymensingh
  3. Ashutosh Shaha Roy, Professor, Department of Nephrology, Principal of Shahid Syed Nazrul Islam Medical College, Kishoregonj
  4. Shamin Ara Begum, Professor, Department of Pharmacology, Community Based Medical College Bangladesh, Mymensingh
  5. Shamima Sattar, Associate Professor, Department of Pharmacology, Community Based Medical College Bangladesh, Mymensingh.
  6. Rfika Afrose, Associate Professor, Department of Pharmacology, Community Based Medical College Bangladesh, Mymensingh.
  7. Jannatul Ferdous, Assistant Professor, Department of Pharmacology, Community Based Medical College Bangladesh Mymensingh.
  8. Sultana Razia, Assistant Professor, Department of Pharmacology, Community Based Medical College Bangladesh, Mymensingh,
  9. Mahbuba Azmary Hussain, Lecturer, Department of Anatomy, Jamalpur Medical College, Jamalpur
  10. Tahmina Akhter Banu, Lecturer, Department of Anatomy, Rangpur Medical College, Rangpur

*For correspondence

Abstract

Background: Chronic kidney disease (CKD) is a prevalent non-communicable disease that requires sophisticated medication and polypharmacy. CKD patients need continual medicine, therefore prescribing patterns must be monitored. Managing drugs for CKD patients poses unique challenges, but it also allows healthcare practitioners to improve treatment for this high-risk population.
Objective: To find out the drug prescribing pattern of CKD patients in Nephrology Department of Mymensingh Medical College, Mymensingh.
Methods: This cross-sectional study was conducted at the Department of Pharmacology in collaboration with Department of Nephrology, Mymensingh Medical College Hospital from July 2022 to June 2023. Participants were randomly selected based on predefined inclusion and exclusion criteria. Data were gathered through direct observation of prescriptions and face-to-face interviews with CKD patients attending the Nephrology Outpatient Department.
Results: Most of the patients were above 40 years old and mean age was 54.8 ± 17.8 years of the study subject. Males (55.2%) were predominant than females (44.8%). Maximum patients were CKD stage 4 and 5 (71.6%). Most common antihypertensive was calcium channel blocker (18.8%) followed by beta blocker (15.1%), Diuretics (14.3%) and alpha receptor blocker. Most common antidiabetic drugs were insulin (16.1%), Tab Linagliptin (7.2%) and Tab Gliclazide (6.0%). Statin was prescribed to 18.8% patients as hypolipidemic drug. Most common prescribed vitamin was vitamin D (76.0%). Most common phosphate binders were calcium carbonate (32.6%), calcium acetate (25.5%), calcium acetate along with magnesium carbonate (9.1%). Most common antimicrobials were ceftriaxone (4.7%), followed by cefuroxime (3.9%), nitrofurantoin (3.6%) and azithromycin (2.1%). Most common antiulcerant was esomeprazole (28.1%), followed by pantoprazole (13.3%), rabeprazole (12.5%), omeprazole (5.5%) and dexlansoprazole. Most common hematinic drugs were iron (oral) (16.9%), iron (inj) (10.7%) and folic acid (10.4%). Common erythropoiesis stimulating agents was Erythropoietin alfa (11.5%). Only 0.8% drug was prescribed by generic name, antibiotics were prescribed in 23.2% cases and injection was prescribed in 50.5% cases. From essential drug list 32.5% drugs were prescribed.
Conclusions: Study revealed, most commonly prescribed antidiabetic drugs were insulin (16.1%), Tab Linagliptin (7.2%) and Tab Gliclazide (6.0%). Metformin (1.6%), Empagliflozin (1.0%) and Glimepiride (0.8%) were also prescribed in Nephrology Depertment, Mymensingh Medical College Hospital.

[Shaheed Syed Nazrul Islam Med Col J 2025, Jul; 10 (2):85-95]

DOI: https://www.doi.org/10.69699/ssnimcj2025v10i2s2

 

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