Tag: Coronary artery bypass grafting

Posted on

ssnimcj2025v10i1s4

Original

Disease Patterns and Outlook with Coronary Artery Bypass Grafting

*Hossain MI,1 Talha MA,2 Tabassum N,3 AhmedY,4 Shadman R,5 Sharifuzzaman M6

 

  1. *Dr. Md. Ibrahim Hossain, Surgical Resident, Department of Cardiac Surgery, NHFH & RI, Darus-Salam, Dhaka, Bangladesh. dr.ebrahim.bd@gmail.com.
  2. Dr. Md. Abu Talha, Registrar, PCICU, NHFH & RI, Darus-Salam, Dhaka, Bangladesh.
  3. Dr. Nazia Tabassum, MPH Fellow, Department of Occupational and Environmental Health (OEH), National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka 1212, Bangladesh.
  4. Dr. Yeahyea Ahmed, MPH Fellow, Department of Maternal and Child Health (MCH), National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka 1212, Bangladesh.
  5. Dr. Rashik Shadman. MPH Fellow, Department of Occupational and Environmental Health (OEH), National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka 1212, Bangladesh.
  6. Dr. Mohammad Sharifuzaman, Senior Consultant, Cardiac Surgery Dept. NHFH & RI, Darus-Salam, Dhaka, Bangladesh.

 

*For correspondence

Abstract

Background: Outcomes of Coronary Artery Bypass Grafting (CABG) are often measured by mortality and morbidity rates. This study aims to analyze disease patterns, graft types, surgical techniques, and post-operative outcomes of CABG, comparing pre-operative findings, past history, and major morbidity and mortality as defined by the Society of Thoracic Surgeons (STS)), USA.

Methods: A retrospective comparative study was conducted with 390 patients, who were underwent CABG. The data were collected from January 2017 to December 2020 where CABG of these patients done within January 2014 to December 2016.

Results: Demographics & Risk Factors: 89.7% were male. No significant differences in BMI or other risk factors distribution (hypertension most common, followed by diabetes, smoking, and hyperlipidemia) (P>0.05). Cardiac Function & Disease Severity: LVEF%: Group A: 51.18 ± 8.76%, Group B: 51.85 ± 8.73% (P>0.05). Triple vessel disease: Group A: 81.5%, Group B: 83.6% (P>0.05). Grafting & Surgery: No significant difference in conduit types or graft use (LAD grafts: Group A: 99%, Group B: 99.5%) (P>0.05). Off-pump surgery was more common (49.49% in Group A, 48.46% in Group B). Postoperative Complications: AKI (Group A: 7.7%, Group B: 16.9%, significant), LOS (Group A: 0.5%, Group B: 4.1%, significant), mortality (Group A: 37.5%, Group B: 62.5%, P>0.05). Surgical Outcome Comparison: Off-pump surgery: mortality 3.4% (13/382), on-pump beating heart surgery: mortality 37.5% (3/8) (P=0.003, significant). Mortality Correlation: Multi-organ failure (strongest predictor), COPD & stroke (moderate), AKI, LOS, EF, old MI, syncope (weak), hyperlipidemia & renal dysfunction (weak). LV dysfunction had a significant negative impact.

Conclusion: Syncope and certain major morbidities differed between the groups, but overall mortality rates were similar. The study highlights specific pre-operative and post-operative factors affecting CABG outcomes.

[Shaheed Syed Nazrul Islam Med Col J 2025, Jan; 10 (1):23-33]

DOI: https://www.doi.org/10.69699/ssnimcj2025v10i1s4

 

Keywords: Disease pattern, Postoperative outcome, Coronary artery bypass grafting, Cardio-vascular diseases.