Original Contribution
Association of Microalbuminuria with Duration of Type-2 Diabetes Mellitus
Haque MJ,1 *Ahammod T,2 Asaduzzaman M,3 Kawsar IA4
- Md. Jahirul Haque, MD, Associate Professor, Department of Medicine; Shaheed Syed Nazrul Islam Medical College, Kishorganj. jahirulhaque69@gmail.com
- *Dr. Tofael Ahammod, MD, Assistant Professor, Department of Nephrology; Shaheed Syed Nazrul Islam Medical College, Kishorganj. ritonahammod@hotmail.com
- Md. Asaduzzaman, FCPS, Senior Consultant (Ophthalmology) and Assistant Director, Mugda Medical College Hospital, Mugda, Dhaka.
- IUM A Kawsar, Assistant Professor, Department of pediatrics, Shaheed Tajuddin Ahmad Medical College, Gazipur.
*For correspondence
Abstract
Background: Microalbuminuria has been linked to the identification of incipient diabetic kidney diseases as well as it is a predictor of outcome in patients with renal disease. It is also an independent risk factor for prediction of cardiovascular morbidity and mortality. In various studies, it was found that long duration of diabetes is associated with higher percentages of microalbuminuria.
Objective: In this study, we tried to correlate microalbuminuria with duration of type 2 diabetes mellitus as well as to observe relation of microalbuminuria in between cardiovascular diseases and without cardiovascular diseases in patients having type 2 diabetes mellitus.
Methods: A hospital based observational study was carried out in the Department of Medicine, Dhaka Medical College & Hospital where total of 100 patients diagnosed as type 2 DM were included. Detailed history including duration of diabetes mellitus, medications received, associated hypertension, any other cardiovascular diseases, and their medication, any history suggestive of adverse cardiac events along with prescribed medication was obtained. Investigations were carried out to assess level of microalbuminuria.
Result: In this study it was observed that 38.0% patients have normoalbuminuria and 62.0% patients have microalbuminuria. It was also observed that presence of microalbuminuria in study population is gradually increasing along with duration of DM and it was high in > 10 years duration of DM group (83.3%). Occurrence of microalbuminuia was found significantly higher (p<0.05) in type 2 DM patients with cardiovascular disease.
Conclusion: Microalbuminuria is an important association with development of cardiovascular diseases in type 2 DM.. Presence of microalbuminuria is gradually increasing along with duration of DM and especially higher in more than 10 years.
[Shaheed Syed Nazrul Islam Med Col J 2024, Jul; 9 (2):54-61]
DOI: https://doi.org/10.69699/ssnimcj2024v9i2a3
Keywords: Microalbuminuria, Type-2 Diabetes Mellitus
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