Tag: Serum sodium

Posted on

ssnimcj2025v10i1s5

Original Article

Changes in Serum Sodium Level in Patients with Acute Myocardial Infarction

 

*Taufiq-Ul-Alam M,1 Diluara K,2 Chowdhury NM,3 Tasnim N,4 Hassan ST,5 Yesmin F6

 

  1. *Dr. Mohammad Taufiq-Ul-Alam, Assistant Professor, Department of Biochemistry, Shaheed Syed Nazrul Islam Medical College, Kishoreganj, Bangladesh, taufiqbd93@gmail.com.
  2. Dr. Khadiza Diluara, Assistant Professor, Department of Biochemistry, President Abdul Hamid Medical College, Kishoreganj, Bangladesh,
  3. Dr. Nafisa Marzan Chowdhury,  Assistant Professor, Department of Biochemistry, Central Medical College, Cumilla, Bangladesh.
  4. Dr. Nafisa Tasnim, Lecturer, Department of Biochemistry, Anwar Khan Modern Medical College, Dhaka, Bangladesh.
  5. Dr. S. M. Tauhid Hassan, Assistant Professor (C.C), Department of Biochemistry, Shaheed Syed Nazrul Islam Medical College, Kishoreganj, Bangladesh.
  6. Dr. Farjana Yesmin, Assistant Professor (C.C), Department of Biochemistry, Shaheed Syed Nazrul Islam Medical College, Kishoreganj, Bangladesh.

 

*For correspondence

Abstract

Background: Acute myocardial infarction (AMI) is defined as the death of cardiac muscle due to prolong ischemia. It is more commonly known as heart attack, is a medical emergency and the leading cause of death for both men and women all over the world. There is a correlation between changes in the serum sodium in acute myocardial infarction. Changes in serum sodium in AMI have not been studied extensively and paucity of information in the literature in this regard.

Objectives: This study was undertaken to evaluate the changes in serum sodium status in patients with acute myocardial infarction.

Methods: The present cross sectional study was carried out in the Department of Biochemistry, Mymensingh Medical College, Mymensingh with the collaboration of the Department of Cardiology, Mymensingh Medical College Hospital, Mymensingh, during the period of July-2019 to June 2020. A total of 100 subjects were included in this study among them, 50 were diagnosed AMI patients denoted as case group & 50 were normal healthy individuals denoted as control group. Serum Sodium was determined by colorimetric method by using electrolyte analyzer for each sample. All statistical analysis was done by using SPSS (statistical package for social science) windows package version 21. P value <0.05 was considered significant.

Results: The mean ± SD values of serum sodium were 136.78 ± 1.63 mmol/L and 130.28 ± 1.82 mmol/L in control group and case group respectively. The analysis showed that, there was highly significant decrease in mean serum sodium level between two groups (p<0.001).

Conclusion: This was a cross sectional study. Analyzing the findings of the present study, highly significant decrease in serum sodium level were observed in AMI patients. A large scale prospective study with the application of more sophisticated technology may be planned to find out the relationship of this biochemical variables with AMI.

[Shaheed Syed Nazrul Islam Med Col J 2025, Jan; 10 (1):34-38]

DOI: https://www.doi.org/10.69699/ssnimcj2025v10i1s5

Keywords: Serum sodium, Acute myocardial infarction