Tag: Type-2 Diabetes Mellitus

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ssnimcj2026v11i2s16

Association of Serum Total Cholesterol with Type 2 Diabetes Mellitus in Bangladeshi Male Adults: A Cross-Sectional Analytical Study
*Mumu NS
*Dr. Naureen Sayeed Mumu, Assistant Professor, Department of Physiology, President Abdul Hamid Medical College and Hospital,Karimganj, Kishoreganj. naureenmumu@gmail.com.  https://orcid.org/0009-0005-3512-8391

Abstract
Introduction: Type 2 Diabetes Mellitus is a chronic metabolic disorder characterized by persistent hyperglycaemia and is often associated with abnormalities in lipid metabolism. Serum total cholesterol is one of the commonly measured lipid parameters and may provide useful information about cardiovascular risk in diabetic patients.
Objective: To evaluate and compare serum total cholesterol levels in Bangladeshi male adults aged above 40 years with Type 2 Diabetes Mellitus and healthy age-matched controls, and to determine the association between elevated cholesterol and diabetic status.
Methods: This cross-sectional analytical study was conducted among 200 Bangladeshi male participants aged above 40 years. Among them, 100 diagnosed Type 2 Diabetes Mellitus patients were included as the study group, and 100 healthy age-matched male individuals were included as the control group. Fasting blood samples were collected after overnight fasting, and serum total cholesterol was measured as the principal biochemical parameter. Data were expressed as mean ± standard deviation, and comparison between groups was performed by unpaired Student’s t test.
Result: The mean serum total cholesterol level was higher in the study group than in the control group, with values of 174.91 ± 45.5 mg/dL and 145.08 ± 31.83 mg/dL, respectively. The mean difference was 29.83 mg/dL, with a t value of 5.37 and p < 0.001. This indicates a statistically highly significant elevation of serum total cholesterol among patients with Type 2 Diabetes Mellitus. The diabetic group also showed approximately 20.56% higher serum total cholesterol than controls.
Conclusion: The findings suggest that elevated serum total cholesterol is an important biochemical abnormality among Bangladeshi male patients with Type 2 Diabetes Mellitus aged above 40 years. However, as this was a cross-sectional study, the result should be interpreted as an association rather than proof of causation or disease progression.

[Shaheed Syed Nazrul Islam Med Col J 2026, July; 11 (2):228-233]
DOI: https://www.doi.org/10.69699/ssnimcj.2026.11.2.16

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Original Contribution

Association of Microalbuminuria with Duration of Type-2 Diabetes Mellitus

 

Haque MJ,1 *Ahammod T,2 Asaduzzaman M,3 Kawsar IA4

 

  1. Md.  Jahirul Haque, MD, Associate Professor, Department of Medicine; Shaheed Syed Nazrul Islam Medical College, Kishorganj. jahirulhaque69@gmail.com
  2. *Dr. Tofael Ahammod, MD, Assistant Professor, Department of Nephrology; Shaheed Syed Nazrul Islam Medical College, Kishorganj. ritonahammod@hotmail.com
  3. Md. Asaduzzaman, FCPS, Senior Consultant (Ophthalmology) and Assistant Director, Mugda Medical College Hospital, Mugda, Dhaka.
  4. IUM A Kawsar, Assistant Professor, Department of pediatrics, Shaheed Tajuddin Ahmad Medical College, Gazipur.

 

*For correspondence

 

Abstract

Background: Microalbuminuria has been linked to the identification of incipient diabetic kidney diseases as well as it is a predictor of outcome in patients with renal disease. It is also an independent risk factor for prediction of cardiovascular morbidity and mortality. In various studies, it was found that long duration of diabetes is associated with higher percentages of microalbuminuria.

Objective: In this study, we tried to correlate microalbuminuria with duration of type 2 diabetes mellitus as well as to observe relation of microalbuminuria in between cardiovascular diseases and without cardiovascular diseases in patients having type 2 diabetes mellitus.

Methods: A hospital based observational study was carried out in the Department of Medicine, Dhaka Medical College & Hospital where total of 100 patients diagnosed as type 2 DM were included. Detailed history including duration of diabetes mellitus, medications received, associated hypertension, any other cardiovascular diseases, and their medication, any history suggestive of adverse cardiac events along with prescribed medication was obtained. Investigations were carried out to assess level of microalbuminuria.

Result: In this study it was observed that 38.0% patients have normoalbuminuria and 62.0% patients have microalbuminuria. It was also observed that presence of microalbuminuria in study population is gradually increasing along with duration of DM and it was high in > 10 years duration of DM group (83.3%). Occurrence of microalbuminuia was found significantly higher (p<0.05) in type 2 DM patients with cardiovascular disease.

Conclusion: Microalbuminuria is an important association with development of cardiovascular diseases in type 2 DM.. Presence of microalbuminuria is gradually increasing along with duration of DM and especially higher in more than 10 years.

[Shaheed Syed Nazrul Islam Med Col J 2024, Jul; 9 (2):54-61]

DOI: https://doi.org/10.69699/ssnimcj2024v9i2a3

 

Keywords: Microalbuminuria, Type-2 Diabetes Mellitus

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