ssnimcj2025v10i1s9

Original

Effect of Pre-existing Ischemic Heart Disease on 30-Days Mortality in COVID-19 Patients

 Iqbal MH,1 *Moontaha H,2 Sarker BK,3 Paul MR,4 Chowdhury AW5

 

  1. Dr. Md. Hasan Iqbal, MBBS, Department of Cardiology, National Institute of Cardiovascular Disease (NICVD), Dhaka, Bangladesh
  2. *Dr. Hashiba Moontaha, MBBS, FCPS (Gynaecology& Obstetrics), Department of Gynaecology& Obstetrics, Dhaka Medical College &Hospital, Dhaka, Bangladesh;hashibapriom@gmail.com
  3. Dr. Bikash Kumar Sarker, Infectious Diseases Hospital, Mohakhali, Dhaka, Bangladesh
  4. Dr. Mira Rani Paul, Rajshahi Medical College Hospital, Rajshahi, Bangladesh.
  5. Professor Dr. Abdul Wadud Chowdhury, Director, National Institute of Cardiovascular Disease, Dhaka, Bangladesh.

 *For correspondence

Abstract

Background: COVID-19 has emerged as a multisystem inflammatory disorder with significant cardiovascular implications. Patients with pre-existing cardiovascular conditions may be particularly vulnerable to severe outcomes, yet data from developing countries regarding the impact of pre-existing ischemic heart disease (IHD) on COVID-19 outcomes remains limited.

Objective: To investigate the effect of pre-existing ischemic heart disease on 30-day mortality in COVID-19 patients at a tertiary care hospital in Bangladesh.

Methods: This case-control study was conducted at Dhaka Medical College Hospital over twelve months, enrolling 120 RT-PCR-confirmed COVID-19 patients (60 with pre-existing IHD, 60 without IHD). Clinical characteristics, laboratory parameters, and treatment modalities were assessed. Outcomes included in-hospital mortality, complications, and 30-day mortality. Data analysis included chi-square tests, t-tests, and multivariable logistic regression.

Results: COVID-19 patients with pre-existing IHD showed significantly higher rates of critical disease (30.0% vs 11.6%, p=0.002), cardiac complications including acute myocardial infarction (45.0% vs 0%, p=0.001), and heart failure (28.3% vs 6.66%, p=0.001). The IHD group required more intensive care (71.6% vs 36.6%, p<0.001) and demonstrated higher in-hospital mortality (36.6% vs 10%, p<0.001) and 30-day mortality (60.0% vs 16.6%, p<0.001). After adjusting for confounders, pre-existing IHD independently predicted 30-day mortality (OR=7.25, 95% CI=2.17-24.23).

Conclusion: COVID-19 patients with pre-existing IHD experience significantly worse outcomes, including higher rates of complications and mortality. These findings emphasize the need for enhanced monitoring and aggressive management strategies for COVID-19 patients with pre-existing IHD in Bangladesh.

[Shaheed Syed Nazrul Islam Med Col J 2025, Jan; 10 (1):63-72]

DOI: https://www.doi.org/10.69699/ssnimcj2025v10i1s9

Keywords: COVID-19, Ischemic Heart Disease, Bangladesh, Mortality, Cardiovascular Complications

ssnimcj2024v9i2a8


Original Contribution

Sociodemographic and Etiological Profile of Patients with Metabolic Acidosis Admitted in an Intensive Care Unit of a Specialized Hospital in Bangladesh

*Rahman MM,1 Islam U,2 Mamun AA3

  1. *Dr. Md Muhibur Rahman, FCPS (Medicine), FCPS (Gastroenterology), Medical Officer, Department of Gastroenterology, Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh. dmc@gmail.com
  2. Ummehoney Islam, MD (Dermatology), Resident, Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh
  3. Abdullah Al Mamun, FCPS (Medicine), Senior Consultant, Department of Medicine, Evercare Hospital, Dhaka, Bangladesh

 

*For correspondence

Abstract

Background: Metabolic acidosis is a serious acid-base disorder frequently encountered in intensive care units (ICUs). Early diagnosis and management of its underlying causes are crucial for improving patient outcomes. However, there is a paucity of local data on the etiologies of metabolic acidosis among critically ill patients in Bangladesh.

Objectives: To determine the causes of metabolic acidosis and distinguish the etiologies associated with an elevated anion gap from those with a normal anion gap among patients admitted to the Medical ICU of a specialized hospital in Bangladesh.

Methods: This hospital-based observational study was conducted at the Medical ICU of Evercare Hospitals, Dhaka, Bangladesh, from March 2012 to August 2012. Fifty patients diagnosed with metabolic acidosis were enrolled. Data on patient demographics, comorbidities, clinical features, and biochemical investigations were collected.

Results: The mean age of patients was 58.04 years, with a predominance of males (68%). Renal failure was the most common cause of metabolic acidosis (58%), followed by lactic acidosis (28%), diabetic ketoacidosis (6%), and methanol poisoning (6%). The majority (82%) had high anion gap metabolic acidosis. Hypoalbuminemia was observed in 62% of patients.

Conclusion: Metabolic acidosis more commonly occurred in patients with renal failure, particularly in the sixth and seventh decades of life, with a male predominance and higher prevalence among individuals from higher socioeconomic backgrounds. Causes of high anion gap metabolic acidosis were more common than normal anion gap acidosis in ICU patients. Prompt diagnosis and management of the underlying etiology are crucial for improving outcomes.

[Shaheed Syed Nazrul Islam Med Col J 2024, Jul; 9 (2):94-102]

doi: https://doi.org/10.69699/ssnimcj2024v9i2a8

Keywords: Metabolic acidosis, anion gap, intensive care unit, Bangladesh, etiology

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ssnimcj2024v9i2a5


Original Contribution

Analysis of Road Traffic Accident Deaths at a Medical College Mortuary in Sylhet

 

*Rahman MF,1 Poly TB,2 Uddin NM,3 Nurunnabi M4

 

  1. Md. Fahmidur Rahman, Assistant Professor, Department of Forensic Medicine and Toxicology, North East Medical College, Sylhet 3100, Bangladesh
  2. Tahmina Begum Poly, Registrar, Department of Obstetrics and Gynaecology, North East Medical College, Sylhet 3100, Bangladesh.
  3. NM Minhaz Uddin, Lecturer, Department of Forensic Medicine and Toxicology, Sylhet MAG Osmani Medical College, Sylhet 3100, Bangladesh.
  4. *Dr. Mohammad Nurunnabi, Assistant Professor, Department of Community Medicine and Public Health, Sylhet Women’s Medical College, Sylhet 3100, Bangladesh. somch@gmail.com

 

*For correspondence

Abstract

Background: Road traffic accidents (RTA) are a widespread global crisis, causing millions of deaths and innumerable injuries each year. It has become more prevalent and deadly as civilization progressed. This study aimed to analyse deaths caused by road traffic accident in Sylhet district.

Methods: A retrospective study, based on autopsy records, was conducted to analyze deaths resulting from road traffic accidents at the mortuary of the Department of Forensic Medicine and Toxicology at Sylhet MAG Osmani Medical College. A total of 301 autopsies were performed from January 2016 to December 2018 at this facility.

Results: The majority of victims, accounting for 48.6%, were adults aged 20-49. Additionally, the death rate was notably higher among individuals aged 60 and older, at 19.6%.The incidence of deaths was higher among males, accounting for 66.1%. Injuries to the skull and scalp region were the most prevalent, occurring in 85.4% of cases, followed by injuries to the brain and spinal cord, which were observed in 76.1% of cases. The most prevalent types of injuries were bruising (92.4%) and abrasions (86.7%). The most common cause of death according to postmortem findings was haemorrhage and shock (91.4%), followed by skull injuries (77.4%) and brain injuries (62.8%).

Conclusion: Addressing these common causes through education, enforcement of traffic laws, infrastructure improvements, and vehicle safety measures can help reduce the number of RTA deaths.

[Shaheed Syed Nazrul Islam Med Col J 2024, Jul; 9 (2):72-78]

DOI: https://doi.org/10.69699/ssnimcj2024v9i2a5

 

Keywords: Road traffic accidents, deaths, Sylhet, Bangladesh.

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SSNIMCJ 2023 v8i 2 a5

Original Contribution

Health Problems among the Agricultural Workers in a Selected Area of
Manikganj District

1. *Dr. Afsana Mahjabin, Associate Professor, Community Medicine, Monno Medical College, Manikganj.
afsana.aqsa@gmail.com
2. Professor Dr. Khondoker Mohammad Ali, Professor, Community Medicine, Monno Medical College, Manikganj
3. Professor Dr. Md. Jahangir Alam, Professor, Community Medicine, Monno Medical College, Manikganj
4. Dr. Mohammad Tariqul Islam, Associate Professor, Physical Medicine & Rehabilitation, Bangabandhu Sheikh
Mujib Medical University, Shahbag, Dhaka
5. Dr. Tamanna Tasneem, Senior Assistant Secretary, Ministry of Information and Broadcasting, Peoples Republic of
Bangladesh
6. Dr. M. A. Muhaimin Al Zihan, Senior Assistant Secretary, Ministry of Public Administration, Peoples Republic of
Bangladesh
*For correspondence

Abstract
Background: Health problems are well recognized problems among the agricultural workers all
over the world specially in developing countries. For an agricultural country like Bangladesh
injuries during cultivation of land are the significant causes of slump. This paper represents the
main causes of agricultural injuries among the Bangladeshi farmers.
Objectives: The study was conducted with an aim to assessing the health problems of the
agricultural workers in a rural area of Manikganj.
Methods: This was a cross-sectional study carried out in different villages of Manikganj during the
period of October, 2022 to March, 2023 by the Department of Community Medicine, Monno
Medical College, Manikganj.
Results: The study revealed that out of 316 respondent’s majorityi.e. 95 (30.66 %) belonged to the
age group (51-60) years. Most of the respondents i. e. 251(52.3%) were male, 89 (28.2%) illiterate
followed by 86 (27.2%) studied up to primary grade. Majority i.e. 144 (45.6%) had monthly family
income (5000-10,000) tk. Regarding duration of agricultural work 210 (66.4%) had been working
for (2-20) years. About 246 (77.4%) had knowledge of occurring physical injury followed by 90
(28.3%)respondents knew about insect bite.Regarding source of injury 150 (47.2%) were injured
by sickle and 111(31.8%) were injured by spade. Regarding common site of injury, majority i. e.
215(67.6%) said that injuries occur in lower limbs and 206 (64.8%) said in upper limb. About 187
(58.8%) respondents injured due to overload of work followed by 126(39.6%) which was due to
lack of knowledge. Regarding preventive measures of health problems 114 (35.9%) farmers used
mathal followed by 120(37.7%) used gamcha. This study revealed that physical injury occurred in
224 (31.9%) farmers followed by heat injury and skin disease in 91(12.9%) & 79(11.3%) farmers
respectively.
Conclusion: Majority of the farmer‘s suffer from different type of injury/accident without taking
necessary preventive measure.

[Shaheed Syed Nazrul Islam Med Col J 2023, Jul; 8 (2):98-106]
Keywords: Health problems, agricultural workers, Manikganj, Bangladesh

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SSNIMCJ 2023 v8 i2 a2

Original Contribution

Forensic Evaluation of Suicidal Deaths due to Organophosphorus Compounds Poisoning

1.Dr. Tasnuva Aziz Munalisa, Assistant Professor, Department of Forensic Medicine, Sylhet Women’s Medical
College, Sylhet 3100, Bangladesh.
2. Dr. Md. Shamsul Islam, Associate Professor and Head, Department of Forensic Medicine, Sylhet MAG Osmani
Medical College, Sylhet 3100, Bangladesh.
3. Dr. Abu Tareq Md Rashel, Assistant Professor, Department of Pharmacology and Therapeutics, Sylhet Women’s
Medical College, Sylhet 3100, Bangladesh.
4. Dr. Tahmina Islam, Assistant Professor, Department of Forensic Medicine, Jalalabad RagibRabeya Medical
College, Sylhet 3100, Bangladesh.
5. *Dr. Mohammad Nurunnabi, Assistant Professor, Department of Community Medicine, Sylhet Women’s Medical
College, Sylhet 3100, Bangladesh. nur.somch@gmail.com
*Correspondence
Abstract
Background: In Bangladesh, agrochemical-related suicides are on the rise. The use of
organophosphorous compounds (OPCs) as insecticides is common and widely used as a suicidal
method in our countries due to their inexpensiveness and easy accessibility.
Methods: The intent of this autopsy study among cases of OPC poisoning deaths was to determine
the evaluation of autopsy reports of 254 OPC poisoning suicidal deaths during 2017 and 2018 at
the mortuary of Sylhet MAG Osmani Medical College, Bangladesh.
Results: Two out of three victims were aged below 30 years, which belongs to the young age
group, and females (58.3%) were predominant. Most of the victims resided in Companygonj
(18.1%), and Gowainghat (15.0%), which represent the rural parts of Sylhet. Three-fourths of the
dead bodies (76.0%) were brought to the morgue under Kotwali police station. The most prevalent
finding of OPC poisoning suicidal deaths was asphyxia (96.8%).
Conclusion: The present study showed that the majority of the patients were young females than
males. The distribution of insecticides to the general population should be strictly regulated by law
and adequate focus placed on the safe usage of pesticides. All age groups need to be made aware of
this poisoning’s potentially fatal effects, but young ones need this information the most.
[Shaheed Syed Nazrul Islam Med Col J 2023, Jul; 8 (2):69-75]
Keywords: Forensic evaluation,OPC poisoning, suicidal deaths, Sylhet, Bangladesh

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SSNIMCJ 2023 v8 i2 a1

Editorial

Deteriorating the Dengue Situation in Bangladesh

Dr. Safia Sultana, MBBS, M Phil (Microbiology), Head & Associate Professor, Department of Microbiology, Shaheed Syed Nazrul Islam Medical College, Kishoreganj.drsafia79@yahoo.com

Abstract: Not available

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